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Faster, cheaper DNA sequencing method developed

In another story from Boston University, researchers have developed a nanoscale sensor that detects DNA molecules as they pass through a 4 nanometer-wide silicon nanopore. The mouth of the nanopore is charged to attract the negatively charged DNA strands. Interestingly, the system works best with long DNA strands which could lead to much faster DNA processing. The system has also decreased by a factor of 10,000 the number of DNA molecules that must be captured so that DNA amplification may not be required, a step that can slow the detection process and introduce transcription errors.

January 2010

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